Epichlorohydrin
Application Notes
Epichorohydrin is used as an acid scavenger in bromination reactions. The preparation of glycidyl ethers, often carried out in two steps, via the ring-opened chlorohydrin ether and subsequent ring-closure with base, can be achieved as a single step, under phase-transfer conditions by the use of epichlorohydrin. Its reaction with primary amines provides a one-step route to 3-azetidinols.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Acid scavenger in bromination reactions
SKU | 02151063-CF |
Alternate Names | (±)-2-(Chloromethyl)oxirane; (±)-Epichlorohydrin; 1-Chloro-2,3-epoxypropane |
Application Notes | Epichorohydrin is used as an acid scavenger in bromination reactions. The preparation of glycidyl ethers, often carried out in two steps, via the ring-opened chlorohydrin ether and subsequent ring-closure with base, can be achieved as a single step, under phase-transfer conditions by the use of epichlorohydrin. Its reaction with primary amines provides a one-step route to 3-azetidinols. |
Auto Ignition | 772° F (USCG, 1999) |
Base Catalog Number | 151063 |
Beilstein Registry Number | 79785 |
Boiling Point | 241.7° F at 760 mm Hg (EPA, 1998) |
CAS # | 106-89-8 |
Density | 1.18 to 1.801 at 68° F (EPA, 1998) |
EC Number | 203-439-8 |
Flash Point | 93° F (EPA, 1998) |
Format | Liquid |
Hazard Statements | H226-H301-H311-H314-H317-H331-H350 |
Melting Point | -54.4 to -14.1° F (EPA, 1998) |
Molecular Formula | C3H5ClO |
Molecular Weight | 92.522 g/mol |
Personal Protective Equipment | Faceshields, full-face respirator, Gloves, Goggles, multi-purpose combination respirator cartridge, respirator filter |
Purity | ≥99% |
Refractive Index | n20/D 1.438 (Lit.) |
RTECS Number | TX4900000 |
Safety Symbol | GHS02, GHS05, GHS06, GHS08 |
Solubility | 50 to 100 mg/mL at 72° F (NTP, 1992) |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Vapor Density | 3.29 (EPA, 1998) (Relative to Air) |
Vapor Pressure | 10 mm Hg at 61.88° F (EPA, 1998) |