5-Chloro-2′-Deoxyuridine
Application Notes
5-Chloro-2′-deoxyuridine (CldU) is used as a thymidine analogue to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors. When used with antibody based immunofluorescent imaging, 5-Chloro-2′-deoxyuridine incorporation may be used in protocols to identify sites of DNA replication. CldU may be used as a labeling substrate in conjunction with other halogenated uridine labeling substrates such as bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU).
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Biochemical | Analogue
SKU | 02105478-CF |
Alternate Names | 5-Chlorodeoxyuridine; CLUDR |
Application Notes | 5-Chloro-2′-deoxyuridine (CldU) is used as a thymidine analogue to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors. When used with antibody based immunofluorescent imaging, 5-Chloro-2′-deoxyuridine incorporation may be used in protocols to identify sites of DNA replication. CldU may be used as a labeling substrate in conjunction with other halogenated uridine labeling substrates such as bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). |
Base Catalog Number | 105478 |
CAS # | 50-90-8 |
Hazard Statements | H302-H312-H332-H351 |
Molecular Formula | C9H11ClN2O5 |
Molecular Weight | 262.646 g/mol |
Personal Protective Equipment | Dust mask , Eyeshields, Gloves |
RTECS Number | YU7400000 |
Safety Symbol | GHS07, GHS08 |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
UV Visible Absorbance | λ max (water): 276 ± 3 nm |