Alamethicin
Application Notes
Alamethicin applications includes increasing [32P] incorporation into phosphatidylinositol 4-phosphate and mermeabilization of sarcoplasmic reticulum vesicles.It causes fusion of lipid vesicles. It has also been used to study membrane interactions of antimicrobial peptides. It catalyzes the exchange of protons for monovalent cations with little difference in affinities and has the ability to transport cations through. It also causes hemolysis of erythrocytes and because it decreases the surface tension of water, it may have use as a detergent.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Increases [32P] incorporation into phosphatidylinositol 4-phosphate | Mermeabilization of sarcoplasmic reticulum vesicles | Fusion of lipid vesicles | Study membrane interactions of antimicrobial peptides | Catalyzes the exchange of protons | Hemolysis of erythrocytes | Detergent
| SKU | 0215900905 |
| Alternate Names | Antibiotic U-22324 |
| Application Notes | Alamethicin applications includes increasing [32P] incorporation into phosphatidylinositol 4-phosphate and mermeabilization of sarcoplasmic reticulum vesicles.It causes fusion of lipid vesicles. It has also been used to study membrane interactions of antimicrobial peptides. It catalyzes the exchange of protons for monovalent cations with little difference in affinities and has the ability to transport cations through. It also causes hemolysis of erythrocytes and because it decreases the surface tension of water, it may have use as a detergent. |
| Base Catalog Number | 2159009 |
| Beilstein Registry Number | 5213858 |
| Biochemical Physiological Actions | Monovalent cation ionophore; can mimic nerve action potential across artificial membranes. Increases the incorporation of 32P into phosphatidylinositol 4-phosphate and sarcoplasmic reticulum vesicles permeability. Causes fusion of lipid vesicles. |
| CAS # | 27061-78-5 |
| Format | Powder |
| Hazard Statements | H301 |
| Molecular Formula | C92H150N22O25 |
| Molecular Weight | 1964.341 g/mol |
| Pack Size | 5 mg |
| Personal Protective Equipment | Eyeshields, Faceshields, Gloves, respirator cartridges |
| Purity | ≥50% |
| RTECS Number | AY1900000 |
| Safety Symbol | GHS06 |
| Source | Trichoderma viride |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
![DS [02159009]](https://www.mpbiochina.com/static/version1714032662/frontend/Mpbio/default/en_US/images/document.png "DS [02159009]")