The 2019 Novel Coronavirus (SARS-CoV-2) is a coronavirus identified as the cause of an outbreak of respiratory illness first detected in Wuhan, China. Its genome encodes four structural proteins, i.e. spike (S), envelope (E), membrane (M) and nucleocapsid (N). The spike protein (S-protein) contains two subunits, S1 and S2. S1 defines the range of the hosts and specificity of the virus, thus recognizes and binds with the cell surface receptor. S2 subunit contains basic elements needed for the membrane fusion. The spike protein is the common target for neutralizing antibodies and vaccines. Synthetic peptide corresponding to Spike S2 subunit aa 1120-1169 was used as immunogen to produce this monoclonal antibody.
Application Notes
Western blot, FACS analysis, Virus neutralization
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
| SKU | 0872041-CF |
| Antibody Type | Monoclonal Antibody |
| Application Notes | Western blot, FACS analysis, Virus neutralization |
| Conjugate | Unconjugated |
| Format | lyophilized |
| Grade | Molecular Grade |
| Host | Mouse |
| Isotype | IgG1 |
| Species Reactivity | SARS-CoV-2 |
| Specificity | Recognizes coronavirus, SARS-CoV-2 spike S2 |
| Storage | Stable for twelve months from date of receipt when stored at -20 °C. Avoid repeated freeze-thaw cycles. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
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