Aprotinin, Cell Culture Grade

Name: Aprotinin, Cell Culture Grade
SKU: 02194559-CF

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Key features and details

Aprotinin

SKU: 02194559-CF

Synonyms

Pancreatic Basic Trypsin Inhibitor, polypeptide; Antagosan; Antikrein; Trasylol; Zymofren; Trypsin inhibitor (basic); Antilysin(e); BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Triazinin

CAS Number:

9087-70-1

Molecular Formula:

C284H432N84O79S7

Molecular Weight:

6511.509 g/mol

EC Number:

232-994-9

MDL Number:

MFCD00130541

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Product Description

Aprotinin

Application Notes

It is used as a proteolytic inhibitor in radioimmunoassays of polypeptide hormones.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Serine protease inhibitor

Specifications

SKU	02194559-CF
Alternate Names	Pancreatic Basic Trypsin Inhibitor, polypeptide; Antagosan; Antikrein; Trasylol; Zymofren; Trypsin inhibitor (basic); Antilysin(e); BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Triazinin
Application Notes	It is used as a proteolytic inhibitor in radioimmunoassays of polypeptide hormones.
Base Catalog Number	194559
Biochemical Physiological Actions	Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or < 3.
CAS #	9087-70-1
EC Number	232-994-9
Extinction Coefficient	E1% (280 nm) = 8.3 (water)(Lit.)
Format	Powder
Grade	Cell Culture Grade
Isoelectric Point	10.5(Lit.)
Melting Point	>100 Â°C
Molecular Formula	C284H432N84O79S7
Molecular Weight	6511.509 g/mol
Personal Protective Equipment	Eyeshields, Gloves, respirator filter
RTECS Number	YN5080000
Source	Bovine Lung
Specific Activity	~4 inhibitor u/mg
Sterilization of Solutions	Sterilization of solutions can be done by filtration through a 0.2 µm filter.
Typical Working Concentration	Effective Concentration is Equimolar with protease (1-2 µg/mL).
Unit Definition	One Kallikrein Inactivating Unit is the quantity of protease inhibitor that has the ability to inhibit 2 Kallikrein units by 50% under optimal conditions.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance	λ max (water) : 277 ± 5 nm