Cathepsin G
Application Notes
Cathepsin G act as a bacteriocidal reagent. Catrhepsin G is often referred to as a chymotrypsin-like enzyme, since it preferentially cleaves proteins on the carboxyl side of leucine, methionine, and phenylalanine. Cathepsin G can be assayed with substrates such as azocasein, Suc-Ala-Ala-Pro-Phe-NPhNO2, and MeOSUC-Ala-Ala-Pro-Met-NPh-NO2. Cathepsin G also has a specificity of action on the oxidized B chain of insulin and on BSA, which indicates a closer similarity to porcine chymotrypsin C than to bovine chymotrypsin A.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Enzymes | Inhibitors | Substrates
| SKU | 02191344-CF |
| Alternate Names | E.C. 3.4.21.20 |
| Application Notes | Cathepsin G act as a bacteriocidal reagent. Catrhepsin G is often referred to as a chymotrypsin-like enzyme, since it preferentially cleaves proteins on the carboxyl side of leucine, methionine, and phenylalanine. Cathepsin G can be assayed with substrates such as azocasein, Suc-Ala-Ala-Pro-Phe-NPhNO2, and MeOSUC-Ala-Ala-Pro-Met-NPh-NO2. Cathepsin G also has a specificity of action on the oxidized B chain of insulin and on BSA, which indicates a closer similarity to porcine chymotrypsin C than to bovine chymotrypsin A. |
| Base Catalog Number | 191344 |
| Biochemical Physiological Actions | Cathepsin G has pro-apoptotic activity and can activate caspases in vitro. |
| CAS # | 107200-92-0 |
| Format | Powder |
| Purity | ≥95% |
| Source | Human Neutrophils |
| Specific Activity | 2 - 4 μ/mg protein |
| Unit Definition | The amount of enzyme that hydrolyzes one µmole of Suc-ala-ala-pro-phe-pNA (1mM) per minute 25 °C in pH 7.5, with 1.6 M NaCl. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
![MP COA [191344] lot ID: 1324F](https://www.mpbiochina.com/static/version1714032662/frontend/Mpbio/default/en_US/images/document.png "MP COA [191344] lot ID: 1324F")