Choline chloride is an organic compound and a quaternary ammonium salt. It is a weak acid. Choline chloride is the salt of the naturally occurring choline, the pre-stage of the neurotransmitter acetylcholine, which is important for mnemonic and thought-processes. Choline occurs naturally in fungi, hop and kingcups and as integral part of lecithin. Choline chloride is a common food additive in animal husbandry
Application Notes
Choline chloride is used as a source of methyl groups for methyl-transfer reactions.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Choline acetyltransferase substrate
SKU | 02194639-CF |
Alternate Names | Choline Hydrochloride; Hepacholine; (2-Hydroxyethyl)Trimethyl-Ammonium Chloride |
Application Notes | Choline chloride is used as a source of methyl groups for methyl-transfer reactions. |
Base Catalog Number | 194639 |
Beilstein Registry Number | 3563126 |
Biochemical Physiological Actions | The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes. |
CAS # | 67-48-1 |
Density | 1.1 g/cm3 at 20 °C (Lit.) |
EC Number | 200-655-4 |
Format | White Crystalline Powder, Hard |
Grade | Cell Culture Grade |
Hazard Statements | H315-H319-H335 |
Melting Point | 302-305 °C (dec.)(lit.) |
Molecular Formula | C5H14NOCl |
Molecular Weight | 139.63 |
Partition Coefficient | n octanol/water (logKow): -3.77 at 25 °C (lit.) |
Personal Protective Equipment | Dust mask, Eyeshields, Gloves |
pH | Neutral to Litmus |
Purity | >99% |
RTECS Number | KH2975000 |
Safety Symbol | GHS08 |
Solubility | Soluble in water: (10% aq soln) Clear, Colorless Solution. |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Vapor Pressure | 10 hPa at 20 °C (Lit.) |