Specifications
| SKU | 0219475105 |
| Alternate Names | α-Lipoic acid; (±)-1,2-Dithiolane-3-pentanoic acid; 6,8-Dithiooctanoic acid; DL-6,8-Thioctic acid; Lip(S<sub>2</sub>); (±)-α-Lipoic acid |
| Base Catalog Number | 19475105 |
| Beilstein Registry Number | 81853 |
| Biochemical Physiological Actions | Antioxidant and coenzyme needed for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. Exogenous thioctic acid is reduced intracellularly by two or more enzymes. The reduced form then influences a number of cell processes by direct radical scavenging, recycling of other antioxidants, increasing glutathione synthesis, and modulating transcription factor activity particularly that of NF-κB. Decreases the phagocytosis of myelin by macrophages. |
| CAS # | 1077-28-7 |
| EC Number | 214-071-2 |
| Grade | Cell Culture Grade |
| Hazard Statements | H302 |
| Molecular Formula | C8H14O2S2 |
| Molecular Weight | 206.3 |
| Pack Size | 5 g |
| Personal Protective Equipment | dust mask, Eyeshields, Gloves |
| Purity | ≥98% |
| RTECS Number | JP1192000 |
| Safety Symbol | GHS07 |
| Solubility | ethanol: soluble (50 mg/mL) |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |