Doxorubicin hydrochloride,≥95%

Name: Doxorubicin hydrochloride,≥95%
SKU: 02159101-CF

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Key features and details

Doxorubicin Hydrochloride

SKU: 02159101-CF

Synonyms

Adriamycin; 14-Hydroxydaunomycin; HCl; DOX; Hydroxydaunorubicin hydrochloride; 14-Hydroxydaunomycin hydrochloride; 10-[(3-Amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl) hydrochloride; Doxorubicin

CAS Number:

25316-40-9

Molecular Formula:

C27H29NO11·HCl

Molecular Weight:

579.983 g/mol

Beilstein Registry Number:

4229251

EC Number:

246-818-3

MDL Number:

MFCD00077757

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Product Description

Doxorubicin Hydrochloride

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Chemotherapeutic agent

Specifications

SKU	02159101-CF
Alternate Names	Adriamycin; 14-Hydroxydaunomycin; HCl; DOX; Hydroxydaunorubicin hydrochloride; 14-Hydroxydaunomycin hydrochloride; 10-[(3-Amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl) hydrochloride; Doxorubicin
Base Catalog Number	159101
Beilstein Registry Number	4229251
Biochemical Physiological Actions	Doxorubicin hydrochloride blocks RNA polymerase and reverse transcriptase. It also inhibits nucleic acid synthesis and induces apoptosis. Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. The fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.
CAS #	25316-40-9
EC Number	246-818-3
Format	Powder
Hazard Statements	H302-H350
Melting Point	399 to 401Â° F (Decomposes) (NTP, 1992)
Molecular Formula	C27H29NO11·HCl
Molecular Weight	579.983 g/mol
Personal Protective Equipment	Eyeshields, Full-face respirator, Gloves, Multi-purpose combination respirator cartridge, Respirator filter
Purity	≥95%
RTECS Number	QI9295900
Safety Symbol	GHS07, GHS08
Solubility	Soluble (NTP, 1992)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure	2.5X10-23 at 25 deg C (est)