Folic acid, >95.0%

Name: Folic acid, >95.0%
SKU: 02101725-CF

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Key features and details

Folic Acid

SKU: 02101725-CF

Synonyms

Pteroylglutamic Acid; N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl] amino]benzoyl]-L-glutamic acid; N-[p-[[(2-amino-4-hydroxy-6-pteridinyl) methyl]amino] benzoyl] glutamic acid; N-(p-[(2-amino-4-hydroxypyrimido[4,5-b]pyrazin-6-yl) methylamino] benzoyl) glutamic acid; PGA; Liver Lactobacillus casei factor; Vitamin Bc; Vitamin M; Folsure; PteGlu

CAS Number:

59-30-3

Molecular Formula:

C19H19N7O6

Molecular Weight:

441.404 g/mol

Beilstein Registry Number:

100781

EC Number:

200-419-0

MDL Number:

MFCD00079305

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Product Description

Folic Acid

Application Notes

Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Cofactors | Enzymes | Inhibitors and Substrates | Folic Acid Metabolism

Specifications

SKU	02101725-CF
Alternate Names	Pteroylglutamic Acid; N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl] amino]benzoyl]-L-glutamic acid; N-[p-[[(2-amino-4-hydroxy-6-pteridinyl) methyl]amino] benzoyl] glutamic acid; N-(p-[(2-amino-4-hydroxypyrimido[4,5-b]pyrazin-6-yl) methylamino] benzoyl) glutamic acid; PGA; Liver Lactobacillus casei factor; Vitamin Bc; Vitamin M; Folsure; PteGlu
Application Notes	Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy.
Base Catalog Number	101725
Beilstein Registry Number	100781
Biochemical Physiological Actions	Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics).
CAS #	59-30-3
EC Number	200-419-0
Extinction Coefficient	9.12, 25.1, 26.9 (0.1 M NaOH)(Lit.)
Format	Powder
Melting Point	482° F (decomposes) (NTP, 1992)
Molecular Formula	C19H19N7O6
Molecular Weight	441.404 g/mol
Personal Protective Equipment	Eyeshields, Gloves, Respirator filter
pH	A suspension of 1 g of folic acid in 10 ml of <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a> has a pH of 4.0-4.8. Aq solutions prepared with <a class="pubchem-internal-link CID-516892" href="https://pubchem.ncbi.nlm.nih.gov/compound/sodium%20bicarbonate">sodium bicarbonate</a> have a pH between 6.5 and 6.8.
pKa	8.26 (Lit)
Purity	>95.0%
RTECS Number	LP5425000
Solubility	Almost insoluble (NTP, 1992)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance	256 ± 3 nm (0.1 N NaOH)
Vapor Pressure	6.2X10-20 mm Hg at 25 deg C /Estimated/