Folinic acid calcium salt, pentahydrate

Name: Folinic acid calcium salt, pentahydrate
SKU: 02191504-CF

CN¥0.00

Key features and details

Folinic Acid Calcium Salt, Pentahydrate

SKU: 02191504-CF

Synonyms

5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt; 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid calcium salt; 5-HCO-H4PteGlu; Calcium folinate; Citrovorum factor calcium salt; Leucovorin calcium salt; N5-Formyl-5,6,7,8- tetrahydropteroyl-L-glutamic acid calcium salt; CF; N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4- hydroxy-6- pteridinyl) methyl] amino] benzoyl] glutamic acid calcium salt; N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl) methyl] amino] benzoyl]-Lglutamic acid calcium salt

CAS Number:

6035-45-6

Molecular Formula:

C20H21N7O7Ca

Molecular Weight:

601.58 g/mol

Beilstein Registry Number:

5723924

EC Number:

216-082-8

Request A Custom or Bulk Quote

Product Description

Folinic Acid Calcium Salt, Pentahydrate

Application Notes

Folinic Acid Calcium Salt, Pentahydrate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications

SKU	02191504-CF
Alternate Names	5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt; 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid calcium salt; 5-HCO-H4PteGlu; Calcium folinate; Citrovorum factor calcium salt; Leucovorin calcium salt; N5-Formyl-5,6,7,8- tetrahydropteroyl-L-glutamic acid calcium salt; CF; N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4- hydroxy-6- pteridinyl) methyl] amino] benzoyl] glutamic acid calcium salt; N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl) methyl] amino] benzoyl]-Lglutamic acid calcium salt
Application Notes	Folinic Acid Calcium Salt, Pentahydrate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer.
Base Catalog Number	191504
Beilstein Registry Number	5723924
Biochemical Physiological Actions	Intermediate product of the metabolism of folic acid; the active form into which that acid is converted in the body, ascorbic acid being a necessary factor in the conversion process.
CAS #	6035-45-6
EC Number	216-082-8
Format	Powder
Hazard Statements	H315-H317-H319-H334-H335
Molecular Formula	C20H21N7O7Ca
Molecular Weight	601.58 g/mol
RTECS Number	MA0600500
Safety Symbol	GHS07, GHS08
Solubility	DMSO Â« 1 (mg/mL)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.