L-Asparagine
Application Notes
L-Asparagine is used in cell culture media and is a component of MEM non-essential amino acids solution. L-Asparagine has been shown to enhance ornithine decarboxylase activity in cultured human colon adenocarcinoma Caco-2 cells and in cultured IEC-6 intestinal epithelial cells. Spore germination in Bacillus subtilis has been increased in the presence of L-asparagine. An isoxazoline RGD mimic platelet GPIIb/IIIa antagonist has been prepared by chiral synthesis with L-asparagine as a starting material. L-Asparagine has been utilized in the synthesis of 4-azalysine building blocks for application to combinatorial chemistry.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Media component | Enhance ornithine decarboxylase activity | Increases spore germination
| SKU | 02194630-CF |
| Alternate Names | (S)-2-Aminosuccinic acid 4-amide; L-Aspartic acid 4-amide ; α-aminoauccinamic acid ; aspartic acid β-amide; Asn; N |
| Application Notes | L-Asparagine is used in cell culture media and is a component of MEM non-essential amino acids solution. L-Asparagine has been shown to enhance ornithine decarboxylase activity in cultured human colon adenocarcinoma Caco-2 cells and in cultured IEC-6 intestinal epithelial cells. Spore germination in Bacillus subtilis has been increased in the presence of L-asparagine. An isoxazoline RGD mimic platelet GPIIb/IIIa antagonist has been prepared by chiral synthesis with L-asparagine as a starting material. L-Asparagine has been utilized in the synthesis of 4-azalysine building blocks for application to combinatorial chemistry. |
| Base Catalog Number | 194630 |
| Beilstein Registry Number | 1723527 |
| CAS # | 70-47-3 |
| Density | 1.543 g/cu cm at 15/4 deg C |
| EC Number | 200-735-9 |
| Format | Powder |
| Grade | Cell Culture Grade |
| Melting Point | 234-235 °C |
| Molecular Formula | C4H8N2O3 |
| Molecular Weight | 132.119 g/mol |
| Optical Rotation | +25° to +36° (c=10, 1N HCl) |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| pKa | 2.14 (-COOH), 8.72 (-NH2)(Lit.) |
| Purity | ≥99% |
| Solubility | Water Solubility29400 mg/L (at 25 °C) |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| Vapor Pressure | 4.8X10-8 mm Hg at 25 deg C (est) |
![MP COA [194630] lot ID: 1956B](https://www.mpbiochina.com/static/version1714032662/frontend/Mpbio/default/en_US/images/document.png "MP COA [194630] lot ID: 1956B")