Product Description
Bleomycin Sulfate
Application Notes
Bleomycin Sulfate is an atineoplastic antibiotic.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
It is used in research as antibiotics; antifungal
Specifications
SKU | 0219030610 |
Alternate Names | Blenoxane; Blexane; Bleo |
Application Notes | Bleomycin Sulfate is an atineoplastic antibiotic. |
Base Catalog Number | 19030610 |
Biochemical Physiological Actions | Bleomycin sulfate binds to DNA, causes ssDNA scission at specific base sequences and inhibits DNA synthesis. This inhibitory action requires bleomycin to bind oxygen and a metal ion. It can also cleave RNA, to a lesser degree but more selectively. It acts as an inducer and regulator of apoptosis and inhibits tumor angiogenesis. |
CAS # | 9041-93-4 |
EC Number | 232-925-2 |
Hazard Statements | H351 |
Melting Point | 71 °C |
Molecular Weight | 1512.619 g/mol |
Pack Size | 10 mg |
Personal Protective Equipment | Eyeshields, Faceshields, full-face particle respirator type, Gloves, respirator |
RTECS Number | EC5991990 |
Safety Symbol | GHS08 |
Solubility | Soluble (NTP, 1992) |
Source | Streptomyces verticillus |
Typical Working Concentration | It is recommended for use as a cell culture agent at 10-100 µg/mL. |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Certificate of Analysis (COA)
Datasheet
Datasheet
Brochures
Brochures
Citations