Carboplatin, 100 mg

Name: Carboplatin, 100 mg
SKU: 0219887380

SKU: 0219887380

Synonyms

cis -Diammine[1,1-cyclobutane-dicarboxylato] platinum; (SP-4-2)-diammine[1,1-cyclobutanedicarboxylato (2-)-O,O']platinum

CAS Number:

41575-94-4

Molecular Formula:

C₆H₁₂N₂O₄Pt

Molecular Weight:

371.25

EC Number:

255-446-0

MDL Number:

MFCD00070464

Packaging size:

100 mg

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Product Description

Carboplatin is a platinum coordination compound and antineoplastic agent that is related to cisplatin.

Application Notes

A study of γ-glutamyltransferase overexpression in carboplatin-treated HeLa cells, with relation to cell defense mechanisms, has been reported. Mouse peritoneal macrophages treated with carboplatin have been shown to produce enhanced IL-1α and TNF-α levels in tissue culture supernatants. A 96 well assay study of the action of carboplatin on 10 human ovarian cancer cell lines has been described.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antineoplastic agent

Specifications

SKU	0219887380
Alternate Names	cis -Diammine[1,1-cyclobutane-dicarboxylato] platinum; (SP-4-2)-diammine[1,1-cyclobutanedicarboxylato (2-)-O,O']platinum
Application Notes	A study of γ-glutamyltransferase overexpression in carboplatin-treated HeLa cells, with relation to cell defense mechanisms, has been reported. Mouse peritoneal macrophages treated with carboplatin have been shown to produce enhanced IL-1α and TNF-α levels in tissue culture supernatants. A 96 well assay study of the action of carboplatin on 10 human ovarian cancer cell lines has been described.
Base Catalog Number	19887380
Biochemical Physiological Actions	Carboplatin is a platinum-based antineoplastic drug that damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell death.
CAS #	41575-94-4
EC Number	255-446-0
Hazard Statements	H302 + H312 + H332-H317-H334-H360
Molecular Formula	C₆H₁₂N₂O₄Pt
Molecular Weight	371.25
Pack Size	100 mg
Personal Protective Equipment	Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter
RTECS Number	TP2300000
Safety Symbol	GHS07, GHS08
Solubility	Very slightly soluble in acetone and alcohol; sparingly soluble in water (10mg/mL-clear, colorless solution).
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure	0.0187 Pa at melting point (Lit.)

Documents

Datasheet

DS [02198873]