Product Description
Antipain Hydrochloride
Application Notes
Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Reversible inhibitor of serine/cysteine proteases
Specifications
SKU | 02152843-CF |
Alternate Names | L-Valinamide; [(S)-1-Carboxy-2-phenylethyl]- carbamoyl-Arg-Val-Arg-al; [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal; [(S)-1-Carboxy-phenethyl]-carbamoyl-Arg-Val-Arg-aldehyde |
Application Notes | Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases. |
Base Catalog Number | 152843 |
Biochemical Physiological Actions | Reversible inhibitor of serine/cysteine proteases and some trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells. |
CAS # | 37682-72-7 |
EC Number | 253-631-0 |
Format | Powder |
Hazard Statements | H302 |
Molecular Formula | C27H44N10O6 (free acid) |
Molecular Weight | 677.629 g/mol |
Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
RTECS Number | YV9350700 |
Safety Symbol | GHS07 |
Typical Working Concentration | Effective concentration is 1 to 100 µM. |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Certificate of Analysis (COA)
Datasheet
Datasheet
Safety Data Sheets
English (United States)
Citations