Compound 48/80

Name: Compound 48/80
SKU: 02159026-CF

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Key features and details

Compound 48/80

SKU: 02159026-CF

CAS Number:

94724-12-6

Molecular Weight:

519.73 g/mol

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Product Description

Compound 48/80

Application Notes

Compound 48/80 used to induce degranulation of GnRH-like immunoreactivity of mast cells in the brain and mesentery and for elucidating the mechanism by which anti-allergic medications suppress conjunctivitis.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Potent histamine releasing agent

Specifications

SKU	02159026-CF
Application Notes	Compound 48/80 used to induce degranulation of GnRH-like immunoreactivity of mast cells in the brain and mesentery and for elucidating the mechanism by which anti-allergic medications suppress conjunctivitis.
Base Catalog Number	159026
Biochemical Physiological Actions	Potent histamine releasing agent, primarily from mast cells, with a subsequent depletion of tissue histamine. It is the action of mast cell mediators on the cardiovascular system that leads to circulatory collapse. The toxicity is due to more than histamine release. It is a potent inhibitor of phospholipase C. Activates G proteins by a mechanism analogous to that of mastorparan. Inhibits calmodulin and human platelet PLC and exhibits a concentration dependent biphasic modulation of human platelet PLA2.
CAS #	94724-12-6
Format	Powder
Hazard Statements	H301-H311-H331
Molecular Weight	519.73 g/mol
Personal Protective Equipment	Eyeshields, Faceshields, Gloves, respirator cartridges
RTECS Number	Gk2402500
Safety Symbol	GHS06
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.