乙醛脱氢酶,Aldehyde dehydrogenase

CN¥1,100.79

Key features and details

From yeast

SKU: 02190679-CF

Synonyms

Aldehyde:NAD[P]+ oxidoreductase; ALDH

CAS Number:

9028-86-8

EC Number:

232-845-3

MDL Number:

MFCD00081306

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Product Description

Aldehyde Dehydrogenase

Application Notes

Aldehyde dehydrogenase oxidizes a number of aliphatic and aromatic aldehydes. Acetyl-GSH is not hydrolyzed.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Acting on aldehydes or oxo groups

Specifications

SKU	02190679-CF
Alternate Names	Aldehyde:NAD[P]+ oxidoreductase; ALDH
Application Notes	Aldehyde dehydrogenase oxidizes a number of aliphatic and aromatic aldehydes. Acetyl-GSH is not hydrolyzed.
Base Catalog Number	190679
Biochemical Physiological Actions	Aldehyde dehydrogenase is a tetramer and has several different isoforms. The enzyme tested in 0.01 M pyrophosphate buffer shows a sharp optimum around pH 9.3 with acetaldehyde as substrate. Potassium ions and cysteine are essential for the enzyme's activity. Rubidium or NH4+ can be substituted for K+, and glutathione for cysteine. Lithium, Na+, and Cs+ inhibit the reaction. Aldehyde dehydrogenase is inhibited by propylurea, crotonaldehyde, n-propyl isocyanate, cyclohexyl isocyanate, 1-n-propyl-1-[(4-chlorophenyl)sulphonyl]-3-n-propylurea, and 1-methyl-1-[(4-chlorophenyl)sulphonyl]-3-n-propylurea. The enzyme may be utilized to quantitate aldehydes present in blood.
CAS #	9028-86-8
EC Number	232-845-3
Extinction Coefficient	9.4 (279 nm)(Lit)
Format	Freeze dried stabilized powder, Potassium Activated
Personal Protective Equipment	Eyeshields, Gloves, respirator filter
Source	Yeast
Specific Activity	Protein-~5 u/mg, solid-≥1 u/mg solid
Unit Definition	One unit causes the oxidation of one µ mole of acetaldehyde to acetic acid per minute at pH 8.0 and 25 °C in the presence of potassium ions and thiols.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.