Trichloroacetic Acid Solution
Application Notes
Trichloroacetic acid is used in protein precipitation; has been used to determine protein concentration by quantitative precipitation. It is also Used as a decalcifier and fixative in microscopy. A protocol for the precipitation of nucleic acids can be found in Molecular Cloning. Rats exposed to chronic sublethal amounts of trichloroacetic acid displayed an increase in serum bilirubin with a decrease in hematological proteins and cholesterols along with significant decreases in red blood corpuscles, mean cell volume, mean corpuscular hemoglobin, hemoglobin and hematocrit. In mice the production of liver tumors was associated to Trichloroacetic acid, which is also a known mouse hepatocarinogen. On the guinea pig trichloroacetic acid was observed to be a mild alergen on the skin.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Decalcifier | Fixative | Determine protein concentration | Precipitation of Proteins
| SKU | 02196057-CF |
| Alternate Names | Trichloroethanoic Acid; TCA; Aceto-caustin; Acide trichloracetique; Acido tricloroacetico; Dow sodium inhibited; Konesta; Trichloressigsaeure; Varitox |
| Application Notes | Trichloroacetic acid is used in protein precipitation; has been used to determine protein concentration by quantitative precipitation. It is also Used as a decalcifier and fixative in microscopy. A protocol for the precipitation of nucleic acids can be found in Molecular Cloning. Rats exposed to chronic sublethal amounts of trichloroacetic acid displayed an increase in serum bilirubin with a decrease in hematological proteins and cholesterols along with significant decreases in red blood corpuscles, mean cell volume, mean corpuscular hemoglobin, hemoglobin and hematocrit. In mice the production of liver tumors was associated to Trichloroacetic acid, which is also a known mouse hepatocarinogen. On the guinea pig trichloroacetic acid was observed to be a mild alergen on the skin. |
| Base Catalog Number | 196057 |
| Beilstein Registry Number | 970119 |
| Boiling Point | 385 to 387° F at 760 mm Hg (NTP, 1992) |
| CAS # | 76-03-9 |
| Density | 1.62 at 77° F (NTP, 1992) |
| EC Number | 200-927-2 |
| Flash Point | greater than 230° F (NTP, 1992) |
| Format | Solution |
| Hazard Statements | H314-H335-H410 |
| Melting Point | 135 to 136° F (NTP, 1992) |
| Molecular Formula | C2HCl3O2 |
| Molecular Weight | 163.378 g/mol |
| pH | pH of 0.1 molar aq solution: 1.2 |
| RTECS Number | AJ7875000 |
| Safety Symbol | GHS05, GHS07, GHS09 |
| Solubility | greater than or equal to 100 mg/mL at 72° F (NTP, 1992) |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| Vapor Density | 5.6 (NTP, 1992) (Relative to Air) |
| Vapor Pressure | 1 mm Hg at 123.8° F ; 5 mm Hg at 168.8° F (NTP, 1992) |
![MP COA [196057] lot ID: 1654C](https://www.mpbiochina.com/static/version1714032662/frontend/Mpbio/default/en_US/images/document.png "MP COA [196057] lot ID: 1654C")