Ethylenediamine Tetraacetic Acid
Application Notes
Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Chelating agent | Buffer Component
| SKU | 02152521-CF |
| Alternate Names | EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil; Ethylenedinitrilotetraacetic acid |
| Application Notes | Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component. |
| Base Catalog Number | 152521 |
| Beilstein Registry Number | 1716295 |
| CAS # | 6381-92-6 |
| EC Number | 200-449-4 |
| Flash Point | Flash point is> 100 deg C, |
| Format | Powder |
| Grade | ACS grade |
| Hazard Statements | H319 |
| Molecular Formula | C10H16N2O8 |
| Molecular Weight | 372.238 g/mol |
| Personal Protective Equipment | Dust mask, Eyeshields, Gloves |
| pKa | 2.0, 2.7, 6.2, 10.3 (Lit.) |
| Purity | ≥99.4% |
| RTECS Number | AH4025000 |
| Safety Symbol | GHS07 |
| Solubility | In <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>, 1.0X10+6 mg/L (miscible) at 25 deg C (est) |
| Typical Working Concentration | EDTA is an inhibitor of metalloproteases and metal-activated proteases at an effective concentration of 1-10 µM. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| Vapor Pressure | 7.57X10-17 mm Hg at 25 deg C (est) |
![MP COA [152521] lot ID: 2866C](https://www.mpbiochina.com/static/version1714032662/frontend/Mpbio/default/en_US/images/document.png "MP COA [152521] lot ID: 2866C")
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