Nystatin, phytopure™

Name: Nystatin, phytopure™
SKU: 02194534-CF

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Key features and details

CAS Number: 1400-61-9

SKU: 02194534-CF

Synonyms

Mycostatin;Fungicidin

CAS Number:

1400-61-9

Molecular Formula:

C₄₇H₇₅NO₁₇

Molecular Weight:

926.10

EC Number:

215-749-0

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Product Description

A polyene antifungal effective against molds, fungi and yeast contamination. It binds to ergosterol and creates nystatin/ergosterol based ion channels in lipid bilayers causing K+ leakage that results in fungal cell death.

Application Notes

Nystatin is a polyene antibiotic. Its uses include preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in TLR2-expressing THP1 cells.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications

SKU	02194534-CF
Alternate Names	Mycostatin;Fungicidin
Application Notes	Nystatin is a polyene antibiotic. Its uses include preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in TLR2-expressing THP1 cells.
Base Catalog Number	194534
Biochemical Physiological Actions	Mode of Action: Nystatin acts by binding to ergosterols in fungal cell membranes, increasing permeability of the membrane, and creating nystatin/ergosterol based ion channels. It also functions as a lipid raft-inhibiting reagent and as membrane associated cholesterol.Antimicrobial spectrum: Neomycin acts against fungi, yeasts and molds.
CAS #	1400-61-9
EC Number	215-749-0
Format	Powder
Grade	Cell Culture Grade
Molecular Formula	C₄₇H₇₅NO₁₇
Molecular Weight	926.10
Personal Protective Equipment	Eyeshields, Gloves, Respirator filter
RTECS Number	RF5950000
Specific Activity	>5000 u/mg
Typical Working Concentration	50 mg/L for yeasts and fungi.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance	290, 305, 320 ± 2 nm( λ max (ethanol))