Paromomycin sulfate, phytopure™

Name: Paromomycin sulfate, phytopure™
SKU: 02194535-CF

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Key features and details

CAS Number: 1263-89-4

SKU: 02194535-CF

CAS Number:

1263-89-4

Molecular Formula:

C₂₃H₄₅N₅O₁₄-H₂SO₄

Molecular Weight:

713.70

Beilstein Registry Number:

5715182

EC Number:

215-031-7

MDL Number:

MFCD00079278

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Product Description

An aminoglycoside antibiotic effective against gram-negative bacteria. Like neomycin, it inhibits protein synthesis by binding to 16s-ribosomal RNA. Useful in studies of cytosine-cytosine (CC) mismatch containing RNAs.

Application Notes

Paromomycin sulfate salt has been used as a• reference compound in antileishmanial activity• RNA-binding ligand and interacts with aptamer. This interaction prevents the binding (and cutting) of dicer to RNA duplex

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications

SKU	02194535-CF
Application Notes	Paromomycin sulfate salt has been used as a• reference compound in antileishmanial activity• RNA-binding ligand and interacts with aptamer. This interaction prevents the binding (and cutting) of dicer to RNA duplex
Base Catalog Number	194535
Beilstein Registry Number	5715182
Biochemical Physiological Actions	Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.
CAS #	1263-89-4
EC Number	215-031-7
Format	Powder
Grade	Cell Culture Grade
Molecular Formula	C₂₃H₄₅N₅O₁₄-H₂SO₄
Molecular Weight	713.70
Potency	>675 µg/mg
Purity	≥97%
RTECS Number	WK2320000
Typical Working Concentration	Paromomycin sulfate is recommended for use in cell culture applications at 100 mg/L.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.