Polymyxin B sulfate, Cell Culture Reagent

Name: Polymyxin B sulfate, Cell Culture Reagent
SKU: 02194538-CF

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Key features and details

Polymyxin B Sulfate

SKU: 02194538-CF

Synonyms

Aerosporin

CAS Number:

1405-20-5

Molecular Formula:

C55H96N16O13·2H2SO4

Molecular Weight:

1301.571 g/mol

EC Number:

215-774-7

MDL Number:

MFCD00131991

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Product Description

Polymyxin B Sulfate

Application Notes

It is used as a lipid A binding agent that induces pore formation in cell membranes and as immobilized (substrate bound) agent for removal of endotoxins. The product has been used clinically to treat infections of the urinary tract, meninges and blood stream caused by susceptible strains of Pseudomonas aeruginosa. It also has uses studying multidrug-resistant pathogens, as an immobilized agent for removal of endotoxins, and to induce pore formation in the membranes of cortex cells from excised sorghum roots.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications

SKU	02194538-CF
Alternate Names	Aerosporin
Application Notes	It is used as a lipid A binding agent that induces pore formation in cell membranes and as immobilized (substrate bound) agent for removal of endotoxins. The product has been used clinically to treat infections of the urinary tract, meninges and blood stream caused by susceptible strains of Pseudomonas aeruginosa. It also has uses studying multidrug-resistant pathogens, as an immobilized agent for removal of endotoxins, and to induce pore formation in the membranes of cortex cells from excised sorghum roots.
Base Catalog Number	194538
Biochemical Physiological Actions	Antibiotic with bactericidal action on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mode of Action: Binds to and interferes with the permeability of the cytoplasmic membrane. Antimicrobial spectrum: Gram-negative bacteria.
CAS #	1405-20-5
EC Number	215-774-7
Format	Powder
Grade	Cell Culture Grade
Hazard Statements	H302
Molecular Formula	C55H96N16O13·2H2SO4
Molecular Weight	1301.571 g/mol
Personal Protective Equipment	Dust mask , Eyeshields, Gloves
Potency	>6,000 u/mg
RTECS Number	TR1150000
Safety Symbol	GHS07
Solubility	Water Solubility25 mg/mL
Typical Working Concentration	50 mg/L
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.