Pyruvic acid, sodium salt, 5 g

Pyruvate, the anion of pyruvic acid, is the end product of the glycolysis pathway, whereby glucose is converted to pyruvate with the production of ATP. In anaerobic organisms such as yeast, pyruvate is converted to ethanol. In gluconeogenesis, pyruvate is converted to glucose. Other metabolic fates of pyruvate include its conversion to alanine by transamination and to oxaloacetate by carboxylation. Pyruvate is involved in respiratory regulation in plants by interacting with alternative oxidase at a conserved cysteine residue. May help prevent hydrogen peroxide mediated cell death.

Application Notes

Sodium pyruvate is utilized as a component in culture broth and media. The use of sodium pyruvate in Wallen fermentation medium to enhance the conversion of oleic acid to 10-ketostearic acid by Bacillus sphaericus has been described. A protocol that uses sodium pyruvate to establish stably transfected human B cell lines has been published.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Metabolic Pathways