An aminoglycoside antibiotic active against gram-positive bacteria. Sisomicin closely resembles gentamicin but is more effective against Pseudomonas aeruginosa and indole-positive Proteus. It interferes with protein synthesis at the level of functional ribosome assembly.
Application Notes
Sisomicin is an aminoglycoside antibiotic isolated from Micromonopora inyoensis. It is effective against most strains of Klebsiellk spp., Escherichia coli, P. aeruginosa, Enterobacter and Proteus spp.. It is a potential treatment for conjunctiva. It is used in disk and tube dilution sensitivity test.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
| SKU | 02156626-CF |
| Alternate Names | Antibiotic 66-40 Sulfate; Extramycin; Mensiso; Pathomycin; Sisomicin Sulfate; Sisomin; Rickamicin Sulfate |
| Application Notes | Sisomicin is an aminoglycoside antibiotic isolated from Micromonopora inyoensis. It is effective against most strains of Klebsiellk spp., Escherichia coli, P. aeruginosa, Enterobacter and Proteus spp.. It is a potential treatment for conjunctiva. It is used in disk and tube dilution sensitivity test. |
| Base Catalog Number | 156626 |
| Biochemical Physiological Actions | Sisomicin interferes with protein synthesis at the level of functional ribosome assembly. The mechanism is similar to that of gentamycin. Sisomicin closely resembles gentamicin but is more effective against Pseudomonas aeruginosa and indole-positive Proteus. |
| CAS # | 53179-09-2 |
| EC Number | 258-414-4 |
| Format | Powder |
| Hazard Statements | H312-H332-H360 |
| Molecular Formula | 2C19H37N5O7-5H2SO4 |
| Molecular Weight | 1385.40 |
| Personal Protective Equipment | Eyeshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter |
| Potency | ~600 µg/mg |
| RTECS Number | WK2288000 |
| Safety Symbol | GHS07, GHS08 |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
![MP COA [156626] lot ID: 1729J](https://www.mpbiochina.com/static/version1714032662/frontend/Mpbio/default/en_US/images/document.png "MP COA [156626] lot ID: 1729J")