Streptomycin sulfate

Name: Streptomycin sulfate
SKU: 02100556-CF

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Key features and details

Streptomycin Sulfate

SKU: 02100556-CF

Synonyms

Streptomycin Sesquisulfate; O-2-Deoxy-2-(methylamino)-a-L- glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-a-L- lyxofuranosyl- (1->4)- N,N'- bis(aminoiminomethyl)-D-streptamine; Streptomycin A

CAS Number:

3810-74-0

Molecular Formula:

C42H84N14O36S3

Molecular Weight:

1457.376 g/mol

Beilstein Registry Number:

3894995

EC Number:

223-286-0

MDL Number:

MFCD00037023

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Product Description

Streptomycin Sulfate

Application Notes

Streptomycin Sulfate is used to inhibit bacterial protein synthesis at the level of initiation inhibition. It inhibits gram-negative and gram-positive bacteria.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications

SKU	02100556-CF
Alternate Names	Streptomycin Sesquisulfate; O-2-Deoxy-2-(methylamino)-a-L- glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-a-L- lyxofuranosyl- (1->4)- N,N'- bis(aminoiminomethyl)-D-streptamine; Streptomycin A
Application Notes	Streptomycin Sulfate is used to inhibit bacterial protein synthesis at the level of initiation inhibition. It inhibits gram-negative and gram-positive bacteria.
Base Catalog Number	100556
Beilstein Registry Number	3894995
Biochemical Physiological Actions	Mode of Action: Inhibits prokaryote protein synthesis. Binds to S12 protein of 30S ribosomal subunit, preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding or inhibiting initiation. Mode of Resistance: Mutation in rpsL (gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Aminoglycoside phosphotransferase also inactivates. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
CAS #	3810-74-0
EC Number	223-286-0
Format	Powder
Half Life	half-life in plasma is about 2-4 hours
Hazard Statements	H302-H361
Molecular Formula	C42H84N14O36S3
Molecular Weight	1457.376 g/mol
Optical Rotation	-77 to -79 ° (c=1% in H2O, 25 °C) (lit.)
Personal Protective Equipment	Dust mask, Eyeshields, Faceshields, Gloves
RTECS Number	WK4990000
Safety Symbol	GHS07, GHS08
Solubility	greater than or equal to 0.1 mg/mL at 64Â° F (NTP, 1992)
Specific Activity	≥650 u/mg
Typical Working Concentration	Typically used at a concentration of 50-100 mg/liter
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.