Tetracycline, hydrochloride, cell culture reagent

Name: Tetracycline, hydrochloride, cell culture reagent
SKU: 02194542-CF

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Key features and details

Tetracycline Hydrochloride

SKU: 02194542-CF

Synonyms

Achromycin HCl; Polucycline HCl; [4S-(4a, 4aa, 5aa, 6b, 12aa)]- 4-(Dimethylamino)- 1, 4, 4a, 5, 5a, 6-11, 12a- octahydro-3, 6, 10, 12, 12a-pentahydroxy- 6- methyl-1, 11-dioxo-2-naphthacenecarboxamide hydrochloride; Achro; Achromycin;, Achromycin V;, Ala Tet; Ambracyn; Ambramicina; Bristaciclina; Cefracycline; Criseociclina; Cyclopar; Diocyclin; Helvecyclin; Hostacyclin; Imex; Mediletten; Mephacyclin; Panmycin; Partrex; Polycycline; Purocyclina; Quadracyclin; Remicyclin; Riocyclin; Ro-Cycline; Sanclomycine; Steclin; Sumycin; Supramycin; Sustamycin; Tefilin; Tetrabakat; Tetrabid; Tetrablet; Tetrabon; Tetrachel; Tetracompren; Tetracyn; Tetrakap; Tetralution; Tetramavan; Tetramycin; Tetrosol; Topicycline; Totomycin; Triphacyclin; Unicin; Vetquamycin-324

CAS Number:

64-75-5

Molecular Formula:

C22H24N2O8·HCl

Molecular Weight:

480.898 g/mol

Beilstein Registry Number:

3844873

EC Number:

200-593-8

MDL Number:

MFCD00078142

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Product Description

Tetracycline Hydrochloride

Application Notes

Tetracycline hydrochloride is used in tetracycline controlled gene expression systems (gene switches) such a the tet-on and tet-off systems.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Used in tetracycline controlled gene expression systems

Specifications

SKU	02194542-CF
Alternate Names	Achromycin HCl; Polucycline HCl; [4S-(4a, 4aa, 5aa, 6b, 12aa)]- 4-(Dimethylamino)- 1, 4, 4a, 5, 5a, 6-11, 12a- octahydro-3, 6, 10, 12, 12a-pentahydroxy- 6- methyl-1, 11-dioxo-2-naphthacenecarboxamide hydrochloride; Achro; Achromycin;, Achromycin V;, Ala Tet; Ambracyn; Ambramicina; Bristaciclina; Cefracycline; Criseociclina; Cyclopar; Diocyclin; Helvecyclin; Hostacyclin; Imex; Mediletten; Mephacyclin; Panmycin; Partrex; Polycycline; Purocyclina; Quadracyclin; Remicyclin; Riocyclin; Ro-Cycline; Sanclomycine; Steclin; Sumycin; Supramycin; Sustamycin; Tefilin; Tetrabakat; Tetrabid; Tetrablet; Tetrabon; Tetrachel; Tetracompren; Tetracyn; Tetrakap; Tetralution; Tetramavan; Tetramycin; Tetrosol; Topicycline; Totomycin; Triphacyclin; Unicin; Vetquamycin-324
Application Notes	Tetracycline hydrochloride is used in tetracycline controlled gene expression systems (gene switches) such a the tet-on and tet-off systems.
Base Catalog Number	194542
Beilstein Registry Number	3844873
Biochemical Physiological Actions	Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. Mode of Resistance: Loss of cell wall permeability.
CAS #	64-75-5
EC Number	200-593-8
Extinction Coefficient	EMm (220nm) = 13 (free base in 0.1 M HCl); EmM (268nm) = 18.04 (free base in 0.1 M HCl); EmM (355nm) = 13.32 (free base in 0.1 M HCl)(Lit.)
Format	Powder
Grade	Cell Culture Grade
Hazard Statements	H315-H319-H335
Melting Point	417Â° F (decomposes) (NTP, 1992)
Molecular Formula	C22H24N2O8·HCl
Molecular Weight	480.898 g/mol
Optical Rotation	-239 ° to -258 ° (c=0.01, 0.1 N HCl)
Personal Protective Equipment	Dust mask, Eyeshields, Gloves
pH	3.0-7.0 /saturated solution/
pKa	pKa (50% aq DMF): 8.3, 10.2 (Lit.)
Potency	≥900 µg/mg
RTECS Number	QI9100000
Safety Symbol	GHS07
Solubility	50 to 100 mg/mL at 72Â° F (NTP, 1992)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance	λ max (1N HCl) 219, 271, 357 ± 5 nm